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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASH1L All Species: 27.27
Human Site: Y2833 Identified Species: 60
UniProt: Q9NR48 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NR48 NP_060959.2 2969 332790 Y2833 P H Y V P D N Y K R N G G R S
Chimpanzee Pan troglodytes XP_513861 2964 332149 Y2828 P H Y V P D N Y K R N G G R S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851926 2974 332800 Y2838 P H Y V P D N Y K R N G G R S
Cat Felis silvestris
Mouse Mus musculus Q99MY8 2958 331289 Y2822 P H Y V P D N Y K R N G G R S
Rat Rattus norvegicus NP_001101159 2918 326454 Y2782 P H Y V P D N Y K R N G G R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511389 1395 154154 K1285 K R R G R P R K Q P L P F D E
Chicken Gallus gallus XP_422858 2954 330578 Y2818 P H Y V P D N Y K R N G G R S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_692254 2962 327377 Y2780 P H Y V P D N Y K R N G G R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW15 2226 246247 L2116 T R K Q K T E L D V G A G P T
Honey Bee Apis mellifera XP_001122948 2180 246181 Q2070 P H S L E G I Q I G S K M N K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784903 3312 363645 H3185 T P H Y I P E H F K R Q Q R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 94.1 N.A. 91.7 91.2 N.A. 21.5 79.9 N.A. 40.9 N.A. 26.1 26 N.A. 27.3
Protein Similarity: 100 99.6 N.A. 97 N.A. 95.3 94.4 N.A. 31.8 89.2 N.A. 53 N.A. 42.2 43.9 N.A. 43.3
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 0 100 N.A. 100 N.A. 6.6 13.3 N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 6.6 100 N.A. 100 N.A. 13.3 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 64 0 0 10 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 10 0 19 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % F
% Gly: 0 0 0 10 0 10 0 0 0 10 10 64 73 0 0 % G
% His: 0 73 10 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 10 0 10 0 0 0 0 0 0 % I
% Lys: 10 0 10 0 10 0 0 10 64 10 0 10 0 0 10 % K
% Leu: 0 0 0 10 0 0 0 10 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 64 0 0 0 64 0 0 10 0 % N
% Pro: 73 10 0 0 64 19 0 0 0 10 0 10 0 10 0 % P
% Gln: 0 0 0 10 0 0 0 10 10 0 0 10 10 0 0 % Q
% Arg: 0 19 10 0 10 0 10 0 0 64 10 0 0 73 0 % R
% Ser: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 64 % S
% Thr: 19 0 0 0 0 10 0 0 0 0 0 0 0 0 19 % T
% Val: 0 0 0 64 0 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 64 10 0 0 0 64 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _